Nature Medicine, Published online: 16 September 2026; doi:10.1038/s41591-026-04662-6 Sex-specific biological aging clocks across multiple organs and molecular systems show that female and male aging patterns can differ in organ-specific…
Nature Medicine, Published online: 16 September 2026; doi:10.1038/s41591-026-04636-8 In this single-arm phase 1 trial, an AAV gene therapy carrying the Padua variant of factor IX was well tolerated in 11 adolescents with hemophilia B and led to…
Nature Medicine, Published online: 16 September 2026; doi:10.1038/s41591-026-04625-x In a prospective study involving 1,785 individuals from four countries, the PANXEON exosome-based biomarker, combined with carbohydrate antigen 19-9 levels…
Nature Medicine, Published online: 16 September 2026; doi:10.1038/s41591-026-04665-3 Increased expression of EBV reactivation genes in B cells and MS risk genes targeted by the EBV protein EBNA-2 precedes MS attacks, linking EBV reactivation and…
NEW YORK — Pennsylvania officials have reported a fourth measles-associated death. The latest death involved an 18-year-old resident of Mifflin County, in the center of the state, the county coroner’s office said in a Facebook post. The cause was…
Simply smelling chocolate helped men complete more leg extension repetitions without making the workout feel harder, with dark chocolate producing the strongest effect. The researchers think familiar food aromas may influence appetite and…
You’re reading the web edition of D.C. Diagnosis, STAT’s twice-weekly newsletter about the politics and policy of health and medicine. Sign up here to receive it in your inbox on Tuesdays and Thursdays. After ProPublica reported that a Russian…
A Medicare experiment in paying for technology to help people manage chronic conditions has just barely gotten underway, and officials are already moving to expand it. Announced last year, the ACCESS model will pay approved companies to manage…
Scientists have uncovered sweeping changes in how the human brain controls and organizes its genome beginning in midlife, offering new clues to why aging sharply increases the risk of Alzheimer’s and other neurodegenerative diseases. One of the…
WASHINGTON — The Food and Drug Administration is opening applications for a pilot program designed to shorten the amount of time it takes for drugmakers to begin testing their products in humans, the agency announced Tuesday. The pilot was first…
Want to stay on top of the science and politics driving biotech today? Sign up to get our biotech newsletter in your inbox. Good morning. I was devastated to find out that we’ll no longer get sunsets after 7 p.m. until next spring. The need-to-know…
Rise and shine, everyone, another busy day is on the way. And it is getting off to a pleasant start here on the Pharmalot campus, where clear blue skies and comfy breezes are greeting us. As for the official mascots, they are happily snoozing in…
Get your daily dose of health and medicine every weekday with STAT’s free newsletter Morning Rounds. Sign up here. Hello, I’m Amanda Erickson! For the past year, I’ve been editing Morning Rounds. Now, I’ll be writing the newsletter twice a week, on…
The flesh eating New World screwworm has returned to the United States, threatening livestock, wildlife, pets and potentially people as it spreads north. A new UC San Diego tracking system aims to predict where the parasite could strike next while…
Vera Therapeutics said Tuesday that its recently approved drug Trutakna stabilized kidney function and reduced the risk of kidney-related death and other complications in patients with a chronic autoimmune kidney disease, according to final…
Spaceflight is a risky business. Keeping astronauts healthy, especially their hearts, has driven Benjamin Levine’s career as a top consulting cardiologist to NASA. Now that a Mars mission is on the horizon, his most recent research continues to…
When I became the first executive director of the country’s oldest statewide tobacco control coalition in 1999, conversations were already underway about how Colorado should spend its share of funds distributed to states from the landmark tobacco…
The rollout of a Medicare program that uses artificial intelligence to approve or deny care was hasty and error-ridden, according to more than a thousand pages of recently released documents and data. The pilot program, called the Wasteful and…
A major analysis of 139 clinical trials involving nearly 10,000 people suggests that some of the simplest treatments may work best for knee osteoarthritis. Knee braces ranked highest overall for reducing pain, stiffness, and mobility problems…
A newly discovered communication system in the microscopic “antennae” of cells may help explain how some congenital heart defects develop. When genetic mutations disrupt this system, the effects may extend beyond the heart to organs including the…
Ancient DNA reveals that plague was already killing hunter-gatherers in Siberia 5,500 years ago, long before cities and flea-driven epidemics. The prehistoric strains may have been especially dangerous because they carried a genetic factor capable…
Nature Medicine, Published online: 15 September 2026; doi:10.1038/s41591-026-04559-4 In a phase 1 trial evaluating GFH375, an oral, dual on–off binding KRAS G12D inhibitor, in patients with KRASG12D-mutated solid tumors, there was one…
Nature Medicine, Published online: 15 September 2026; doi:10.1038/s41591-026-04610-4 Two early clinical studies of selective KRASG12D inhibitors show encouraging activity in advanced cancers with G12D mutations, signaling a transformative change in…
Nature Medicine, Published online: 15 September 2026; doi:10.1038/s41591-026-04644-8 In the phase 2 RIO trial, there was delayed viral rebound and resistance to broadly neutralizing antibodies 3BNC117-LS and 10-1074-LS in adult males living with…
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